Radiofrequency irradiation attenuates angiogenesis and inflammation in UVB-induced rosacea in mouse skin
Rosacea is a skin inflammatory condition accompanied by cutaneous signs such as oedema, flushing, erythema, telangiectasia and pustules. Generally, rosacea is triggered by ultraviolet B (UVB) exposure. When exposed to UVB, skin epidermis thickens and produces elevated levels of pro-inflammatory cytokines, especially keratinocyte-related VEGF, a potent angiogenic factor. The upregulations of VEGF expression and its secretion promote the formation of new blood vessels and exacerbates rosacea.
Original Article Source Credits: Wiley Online Library , https://onlinelibrary.wiley.com/
Article Written By: Myeongjoo Son,Joonhong Park,Seyeon Oh,Junwon Choi,Minjung Shim,Donghwan Kang,Kyunghee Byun
Original Article Posted on: 20 May 2020
Link to Original Article: https://onlinelibrary.wiley.com/doi/abs/10.1111/exd.14115